| |
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Microscale dysfunction and mesoscale compensation in degenerating neuronal networks |
退化神经元网络中的微尺度功能障碍与中尺度代偿 |
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|
| |
小鼠脑片 |
Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency |
CXCR4相关原发性免疫缺陷中结构和精神运动缺陷的神经发育起源 |
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| |
小鼠胚胎干细胞，来源的背侧端脑（DT）和腹侧端脑（VT）祖细胞衍生的神经元， |
A proper excitatory/inhibitory ratio is required to develop synchronized network activity in mouse cortical cultures |
在小鼠皮质培养物中，需要适当的兴奋/抑制比率来产生同步的网络活动 |
|
|
| |
阿尔茨海默 |
Network-Level Characterization of Hippocampal Disruptions in Alzheimer’s Disease Using Large-Scale Electrophysiology |
利用大规模电生理学对阿尔茨海默病中海马体功能障碍的网络水平特征进行研究 |
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| |
癫痫患者脑片 |
Organotypic human brain slice cultures as a translational testing platform for novel neuromodulation devices |
人类脑器官型切片培养物作为新型神经调节装置的转化测试平台 |
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| |
胚胎干细胞衍生的人脑类器官 |
Intermittent Propofol Exposure Induces Neurodevelopmental Alterations in Human Brain Organoids |
间歇性丙泊酚暴露会导致人脑类器官神经发育改变 |
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| 方法 |
神经肌肉类器官 |
Human neuromuscular organoids mimic cancer-induced muscle cachexia |
人类神经肌肉类器官模拟癌症诱发的肌肉恶病质 |
2026年2月23日 |
Cell Reports Methods |
| 方法 |
神经元培养物 |
Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles |
引导性和非引导性前脑类器官的多组学分析揭示了细胞组成和代谢谱的差异 |
2026 年 02 月 23 日 |
Cell Reports Methods |
| - |
脊髓类器官与脑类器官 (来自 SMA 患者诱导多能干细胞) |
Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids |
靶向反义寡核苷酸治疗挽救脊髓性肌萎缩症类器官的发育异常 |
2025 年 12 月 21 日 |
Nature Communications |
| 方法 |
高密度微电极阵列 (HD-MEA) 结合 PDMS 微结构的体外神经元网络 |
Protocol for tailored in vitro neuronal networks on high- density microelectrode arrays with polydimethylsiloxane microstructures |
基于聚二甲基硅氧烷微结构的高密度微电极阵列定制化体外神经元网络实验方案 |
2026 年 3 月 20 日 |
STAR Protocols |
| 6 孔文献 |
人类诱导多能干细胞 (hiPSC) 衍生神经元类器官 |
A Layered Approach to Secure the Safety and Graft-Host Integration of hiPSC-derived Functionalized Neuronal Tissueoid for Repair after Complete Spinal Cord Injury in Rats |
一种确保人类诱导多能干细胞衍生功能化神经元类器官安全性及移植物 - 宿主整合的分层方法在大鼠完全性脊髓损伤修复中的应用 |
未明确 (预印本) |
SSRN (未同行评审) |
| 6 孔文献 |
人类脑组装体 (皮质 - 纹状体组装体) |
Autism-associated SCN2A deficiency disrupts cortico- striatal circuitry in human brain assembloids |
自闭症相关 SCN2A 缺陷破坏人类脑组装体中的皮质 - 纹状体环路 |
未明确 (预印本) |
bioRxiv (未同行评审) |
| 6 孔文献 |
人类脑组装体 (中脑 - 纹状体组装体) |
Human microglia in brain assembloids display region- specific diversity and respond to hyperexcitable neurons carrying SCN2A mutation |
脑组装体中的人类小胶质细胞呈现区域特异性多样性并对携带 SCN2A 突变的过度兴奋神经元产生应答 |
未明确 (预印本) |
bioRxiv (未同行评审) |
| 6 孔文献 |
人类多能干细胞 (hPSC) 模型 ( ventral forebrain progenitors、GABAergic 神经元等) |
Tatton-Brown- Rahman-Syndrome- associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function |
Tatton-Brown- Rahman 综合征相关 DNMT3A 突变解除皮质中间神经元分化抑制并破坏神经元网络功能 |
未明确 (预印本) |
bioRxiv (未同行评审) |
| 6 孔文献 |
人类诱导多能干细胞衍生神经元 (谷氨酸能、GABA 能) 和星形胶质细胞共培养体系 |
Modulation of Glutamatergic Burst Activity by Hydrolysed Arabinoxylan Rice Bran: A Multielectrode Array Study in Human-Induced Pluripotent Stem Cell-Derived Neurones and Astrocytes |
水解阿拉伯木聚糖米糠对谷氨酸能爆发活动的调节：基于人类诱导多能干细胞衍生神经元和星形胶质细胞的多电极阵列研究 |
2025 年 1 月 20 日 |
Cureus |
| 6 孔文献 |
人类诱导多能干细胞衍生神经元网络 (纯谷氨酸能、谷氨酸能 + GABA 能混合) |
Electrical and chemical modulation of homogeneous and heterogeneous human-iPSCs- derived neuronal networks on high density arrays |
高密度阵列上同源和异源人类诱导多能干细胞衍生神经元网络的电调制和化学调制 |
2024 年 2 月 6 日 |
Frontiers in Molecular Neuroscienc |
| - |
神经元培养物 |
Protocol for the enhanced analysis of electrophysiological data from high- density multi- electrode arrays with nicespike and spikeNburst |
利用 nicespike 和 spikeNburst 增强高密度多电极阵列电生理数据分析的方案 |
2025 |
STAR Protoc. |
| - |
神经元培养物 |
From Neural Activity to Computation: Biological Reservoirs for Pattern Recognition in Digit Classification |
从神经活动到计算：用于数字分类模式识别的生物储备池 |
2025 |
ICCV |
| - |
神经元培养物 |
Criticality in neural cultures: Insights into memory and connectivity in entorhinal- hippocampal networks |
神经培养物中的临界性：内嗅 - 海马网络中记忆与连接性的见解 |
2025 |
Chaos Solit. Fractals |
| - |
急性脑切片 |
High-density multielectrode array (MEA) recordings in a rodent glioma model |
啮齿动物胶质瘤模型中的高密度多电极阵列 (MEA) 记录 |
2025 |
J. Neurosci. Methods |
| - |
急性脑切片 |
A novel prefrontal cortex and hippocampus combined brain slice based on in vivo diffusion tensor imaging of healthy male rats |
基于健康雄性大鼠在体扩散张量成像的前额叶皮层 - 海马联合脑切片新模型 |
2025 |
Neurosci. Lett. |
| - |
视网膜 |
Saltatory axonal conduction in the avian retina |
鸟类视网膜中的跳跃式轴突传导 |
2025 |
J. Physiol. |
| - |
视网膜 |
Filter-based models of suppression in retinal ganglion cells: Comparison and generalization across species and stimuli |
视网膜神经节细胞抑制的基于滤波器模型：跨物种与刺激的比较及泛化 |
2025 |
PLoS Comput Biol |
| - |
视网膜 |
Spatial distribution and functional integration of displaced retinal ganglion cells |
移位视网膜神经节细胞的空间分布与功能整合 |
2025 |
Sci. Rep. |
| - |
视网膜 |
Homologous amacrine to amacrine gap junction coupling serves communication between neighbour OFF alpha retinal ganglion cells |
同源无长突细胞间的缝隙连接偶联介导相邻 OFFα 视网膜神经节细胞间的通讯 |
2025 |
Physiol. J. |
| - |
视网膜 |
Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions |
明视觉条件下含黑视蛋白的视网膜神经节细胞在瞳孔光反射中的关键作用 |
2025 |
Front. Cell. Neurosci. |
| - |
视网膜 |
A membrane- targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina |
膜靶向光开关恢复退化视网膜中对光的生理性 ON/OFF 响应 |
2025 |
Nat. Commun. |
| - |
技术 |
Longitudinal and Noninvasive Intracellular Recordings of Spontaneous Electrophysiological Activity in Rat Primary Neurons on Planar MEA Electrodes |
平面 MEA 电极上大鼠原代神经元自发电生理活动的纵向无创细胞内记录 |
2025 |
Advanced Materials |
| 1 |
神经元培养物 |
Dual inhibition of MAPK/ERK and BMP signaling induces entorhinal-like identity in mouse ESC-derived pallial progenitors |
MAPK/ERK 和 BMP 信号的双重抑制诱导小鼠 ESC 来源的大脑皮层祖细胞获得内嗅样特性 |
2025 |
Stem Cell Reports |
| 2 |
类器官 |
Generation of human nucleus basalis organoids with functional nbM- cortical cholinergic projections in transplanted assembloids |
生成具有功能性 nbM- 皮层胆碱能投射的人源基底核类器官于移植组合体中 |
2025 |
Cell Stem Cell |
| 3 |
类器官 |
Human brain organoids record the passage of time over multiple years in culture |
人脑类器官在长期培养中历时记录 |
- |
预发表文献 |
| 4 |
急性脑切片 |
High Resolution Detection of Stationary and Evolving 2D-Current Source Density within Neuronal Microcircuits |
神经元微环路内静态与动态二维电流源密度的高分辨率检测 |
2025 |
J Neurophysiol. |
| 5 |
急性脑切片 |
Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays |
使用 3D 高密度多电极阵列增强急性脑切片、球体和类器官的电生理记录 |
2025 |
PLoS One |
| 6 |
急性脑切片 |
Unsupervised pipeline for the identification of cortical excitatory and inhibitory neurons in high- density multielectrode arrays with ground- truth validation |
基于高密度多电极阵列和真实值验证的皮质兴奋性和抑制性神经元无监督识别流程 |
2025 |
eLife |
| 7 |
急性脑切片 |
Transplanted human striatal progenitors exhibit functional integration and modulate host circuitry in a Huntington’s disease animal model |
移植的人纹状体祖细胞在亨廷顿病动物模型中展示功能整合并调节宿主电路 |
2025 |
Pharmacological Research |
| 8 |
急性脑切片 |
Dynamic mapping of network-level LTP in the hippocampus via high-resolution bioelectrical sensing |
通过高分辨率生物电传感对海马网络水平长时程增强的动态映射 |
2025 |
APL Bioeng. |
| 9 |
神经元培养 |
The lncRNA Gas5 is an activity- responsive scaffold that mediates cAMP-dependent synaptic plasticity |
lncRNA Gas5 是一种活动响应支架，介导 cAMP 依赖性突触可塑性 |
2025 |
Sci. Signal. |
| 10 |
神经元培养 |
CACNA1A loss-of- function affects neurogenesis in human iPSC-derived neural models |
CACNA1A 功能缺失影响人 iPSC 衍生神经模型中的神经发生 |
2025 |
Cell. Mol. Life Sci. |
| 11 |
急性脑切片 |
Neuro developmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency |
CXCR4 相关原发性免疫缺陷中结构和精神运动缺陷的神经发育起源 |
2025 |
Neuron |
| 12 |
急性脑切片 |
MEA-seqX: High- Resolution Profiling of Large-Scale Electrophysiological and Transcriptional Network Dynamics |
MEA-seqX : 大规模电生理和转录网络动力学的高分辨率分析 |
2025 |
Adv. Sci. |
| 13 |
急性脑切片 |
Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model |
在肌张力障碍动物模型中，苍白球脑深部电刺激通过全网络效应使异常的小脑皮层活动恢复正常 |
2025 |
Neurobiol. Dis. |
| 14 |
急性脑切片 |
High-Quality Seizure- Like Activity from Acute Brain Slices Using a Complementary Metal-Oxide- Semiconductor High- Density Microelectrode Array System |
使用互补金属氧化物半导体高密度微电极阵列系统从急性脑切片中获得高质量的癫痫样活性 |
2024 |
J. Vis. Exp. |
| 15 |
急性脑切片 |
Milestone White Paper 1 |
里程碑白皮书 1 : 从冷冻保存并复温的急性切除啮齿动物神经组织中恢复电活动 |
2024 |
Cradle |
| 16 |
急性脑切片 |
A high-density multi- electrode platform examining the effects of radiation on in vitro cortical networks |
高密度多电极平台研究辐射对体外皮质神经网络的影响 |
2024 |
Scientific Reports |
| 17 |
类器官 |
Generation of human region-specific brain organoids with medullary spinal trigeminal nuclei |
具有髓质脊髓三叉神经核的人类区域特异性脑类器官的生成 |
2024 |
Cell Stem Cell |
| 18 |
类器官 |
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers |
脑嵌合体揭示个体对神经毒性诱因的易感性 |
2024 |
Nature |
| 19 |
类器官 |
Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress |
共济失调毛细血管扩张症患者来源的神经元与脑类器官模型揭示线粒体功能障碍与氧化应激 |
2024 |
Neurobiology of Disease |
| 20 |
急性视网膜 |
Gap junctions fine- tune ganglion cell signals to equalize response kinetics within a given electrically coupled array |
间隙连接通过微调神经节细胞信号，使特定电耦合细胞阵列内的响应动力学趋于均衡 |
2024 |
iScience |
| 21 |
类器官 |
Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2 |
唐氏综合征脑类器官中脉络丛缺陷增强 SARS-CoV-2 的神经嗜性 |
2024 |
Science Advances |
| 22 |
急性脑切片 |
Axon morphology and intrinsic cellular properties determine repetitive transcranial magnetic stimulation threshold for plasticity |
轴突形态与内在细胞特性决定重复经颅磁刺激诱导可塑性的阈值 |
2024 |
Front. Cell. Neurosci. |
| 23 |
神经元培养 |
Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features |
显性 β-catenin 突变导致具有可识别综合征特征的智力障碍 |
2024 |
The Journal of Clinical Investigation |
| 24 |
急性脑切片 |
Recording and Analyzing Multimodal Large- Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array |
基于 CMOS 集成高密度微电极阵列的多模态大规模神经元集群动力学记录与分析 |
2024 |
J. Vis. Exp. |
| 25 |
急性脑切片 |
Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/NaV1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo |
选择性 NaV1.6 及双靶点 NaV1.6/NaV1.2 通道抑制剂的分子药理学研究：体外抑制兴奋性神经元活动的机制 |
2024 |
ACS Chem. Neurosci. |
| 26 (6 孔) |
神经元培养 |
Electrical and chemical modulation of homogeneous and heterogeneous human-iPSCs- derived neuronal networks on high density arrays |
高密度阵列上均质与异质人源诱导多能干细胞分化神经元网络的电化学调控 |
2024 |
Front. Mol. Neurosci. |
| 27 |
神经元培养 |
Combined small- molecule treatment accelerates maturation of human pluripotent stem cell- derived neurons |
小分子联合治疗可加速人类多能干细胞衍生神经元的成熟 |
2024 |
Nature Biotechnology |
| 28 |
急性脑切片 |
Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development |
小胶质细胞 Trem2 表达对发育期神经元生物能量稳态的维持作用 |
2023 |
Immunity |
| 29 |
心肌细胞 |
Multi-chamber cardioids unravel human heart development and cardiac defects |
多腔室心脏类器官揭示人类心脏发育机制与心脏缺陷 |
2023 |
Cell |
| 30 |
急性脑切片 |
Low glycemic index diet restrains epileptogenesis in a gender-specific fashion |
低血糖指数饮食通过性别特异性机制抑制癫痫发生 |
2023 |
Cellular and Molecular Life Sciences |
| 31 |
急性视网膜 |
Platinum Nanozymes Counteract Photoreceptor Degeneration and Retina Inflammation in a Light-Damage Model of Age- Related Macular Degeneration |
铂纳米酶在光损伤模型中抑制年龄相关性黄斑变性的光感受器退行与视网膜炎症 |
2023 |
ACS Nano |
| 32 |
急性脑切片 |
Recording Network- based Synaptic Transmission and LTP in the Hippocampal Network on a Large- scale Biosensor |
基于大规模生物传感器的海马神经网络突触传递与长时程增强记录研究 |
2023 |
IEEE BioSensors Conference |
| 33 |
急性脑切片 |
High-resolution CMOS-based biosensor for assessing hippocampal circuit dynamics in experience- dependent plasticity |
高分辨率 CMOS 生物传感器解析经验依赖性可塑性中的海马环路动态 |
2023 |
Biosensors and Bioelectronics |
| 34 |
急性脑切片 |
Alteration of neural network and hippocampal slice activation through exosomes derived from 5XFAD nasal lavage fluid |
5XFAD 鼻腔灌洗液外泌体对神经网络及海马切片活性的调控作用 |
2023 |
Int. J. Mol. Sci. |
| 35 |
急性视网膜 |
Birds multiplex spectral and temporal visual information via retinal On- and Off- channels |
鸟类视网膜通过 On/Off 通道实现光谱与时间视觉信息的多路传输机制 |
2023 |
Nature Communications |
| 36 |
类器官 |
Light-responsive microRNA molecules in human retinal organoids are differentially regulated by distinct wavelengths of light |
不同波长光调控人视网膜类器官中光响应性 microRNA 分子的差异性表达 |
2023 |
iScience |
| 37 |
急性脑切片 |
Anisotropy and Frequency Dependence of Signal Propagation in the Cerebellar Circuit Revealed by High- Density Multielectrode Array Recordings |
基于高密度多电极阵列记录揭示小脑回路信号传播的各向异性与频率依赖性 |
2023 |
Biomedicines |
| 38 |
心肌细胞 |
Gene-Edited Human- Induced Pluripotent Stem Cell Lines to Elucidate DAND5 Function throughout Cardiac Differentiation |
基因编辑人 iPSC 细胞系解析 DAND5 在心脏分化中的功能调控 |
2023 |
Cells |
| 39 |
急性脑切片 |
Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia |
小脑小胶质细胞促炎性激活通过浦肯野细胞过度兴奋引发共济失调 |
2023 |
Pharmacological Research |
| 40 |
类器官 |
Human-derived cortical neurospheroids coupled to passive, high-density and 3D MEAs: a valid platform for functional tests |
人源皮质神经球体联合被动式高密度 3D 微电极阵列构建功能性验证平台 |
2023 |
Bioengineering |
| 41 |
神经元培养 |
Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture |
Aβ42 寡聚体对原代皮层神经元网络的病理效应研究 |
2023 |
International Journal of Molecular Sciences |
| 42 |
急性脑切片 |
Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression |
PCDH19 嵌合表达条件敲除小鼠模型中神经元网络活动与连接性受损的机制研究 |
2023 |
Molecular Psychiatry |
| 43 |
急性脑切片 |
A deep generative adversarial network capturing complex spiral waves in disinhibited circuits of the cerebral cortex |
深度生成对抗网络解析去抑制皮质回路中复杂螺旋波的动力学特征 |
2023 |
BMC Neuroscience |
| 44 |
急性脑切片 |
An in vitro model of drug-resistant seizures for selecting clinically effective antiseizure medications in Febrile Infection- Related Epilepsy Syndrome |
基于体外耐药性癫痫模型筛选热性感染相关癫痫综合征临床有效抗癫痫药物 |
2023 |
Frontiers in Neurology |
| 45 |
急性脑切片 |
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy |
脂质积累的反应性星形胶质细胞促进癫痫疾病进展的机制研究 |
2023 |
Nature Neuroscience |
| 46 |
其他模型 |
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease |
人多能干细胞来源的骶神经嵴细胞在严重先天性巨结肠症模型中的治疗作用 |
2023 |
Cell Stem Cell |
| 47 |
类器官 |
Incorporating microglia-like cells in human induced pluripotent stem cell- derived retinal organoids |
人类 iPSC 来源视网膜类器官中整合小胶质样细胞的构建与功能验证 |
2023 |
Journal of Cellular and Molecular Medicine |
| 48 |
急性脑切片 |
Network synaptic plasticity of cerebellum in a model of paroxysmal dystonia |
阵发性肌张力障碍模型中小脑网络突触可塑性的机制研究 |
2023 |
Brain Stimulation |
| 49 |
急性视网膜 |
Glial Bmal1 role in mammalian retina daily changes |
胶质细胞 Bmal1 在哺乳动物视网膜昼夜节律调控中的核心作用 |
2022 |
Scientific Reports |
| 50 |
急性脑切片 |
Large-scale Multimodal Recordings on a High-density Neurochip: Olfactory Bulb and Hippocampal Networks |
基于高密度神经芯片的嗅球与海马网络大规模多模态记录研究 |
2022 |
IEEE EMBC |
| 51 |
神经元培养 |
Learning populations with hubs govern the initiation and propagation of spontaneous bursts in neuronal networks after learning |
学习诱导的枢纽神经元群调控神经网络自发爆发的启动与传播 |
2022 |
Frontiers in Neuroscience |
| 52 |
急性脑切片 |
Xenon LFP Analysis Platform Is a Novel Graphical User Interface for Analysis of Local Field Potential From Large-Scale MEA Recordings |
Xenon LFP 分析平台：面向大规模 MEA 记录的局部场电位分析新型图形化界面 |
2022 |
Frontiers in Neuroscience |
| 53 |
急性脑切片 |
Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia |
新生儿苯环利定精神分裂症模型中小脑攀爬纤维 / 浦肯野细胞突触连接的异常重构 |
2022 |
PNAS |
| 54 |
急性视网膜 |
Receptive field estimation in large visual neuron assemblies using a super-resolution approach |
基于超分辨率方法的大规模视觉神经元集群感受野估计算法研究 |
2022 |
Journal of Neurophysiology |
| 55 |
神经元培养 |
Revealing directed effective connectivity of cortical neuronal networks from measurements |
基于测量数据的皮层神经元网络定向有效连接性解析 |
2022 |
APS Physics |
| 56 |
急性脑切片 |
Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain |
缺氧诱导碳酸酐酶介导的脊髓背角神经元活化及其在神经病理性疼痛中的作用机制 |
2022 |
PAIN |
| 57 |
急性脑切片 |
Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics |
多焦点成像与电生理记录揭示小脑网络动态的微环路机制 |
2022 |
Cellular Neuroscience Frontiers in |
| 58 |
急性视网膜 |
A novel approach to the functional classification of retinal ganglion cells |
视网膜神经节细胞功能分类的新方法研究 |
2022 |
Open Biology |
| 59 |
神经元培养 |
Heterogeneous Responses to Changes in Inhibitory Synaptic Strength in Networks of Spiking Neurons |
脉冲神经元网络中抑制性突触强度变化的异质性响应机制 |
2022 |
Cellular Neuroscience Frontiers in |
| 60 |
类器官 |
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina |
人视网膜类器官作为视网膜毒性评估工具的全面验证研究 |
2022 |
Stem Cells Translational Medicine |
| 61 |
急性脑切片 |
Implementation of biohybrid olfactory bulb on a high- density CMOS-chip to reveal large-scale spatiotemporal circuit information |
基于高密度 CMOS 芯片的生物混合嗅球构建揭示大规模时空环路信息 |
2022 |
Biosensors and Bioelectronics |
| 62 |
急性脑切片 |
Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation– Vasoconstriction Competition |
小脑皮层神经血管耦合的非线性频率依赖性揭示血管舒张 - 收缩竞争机制 |
2022 |
Cells |
| 63 |
急性脑切片 |
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis |
三维双光子脑成像揭示双氢青蒿素通过调节铁稳态发挥抗癫痫作用 |
2021 |
Cell Chemical Biology |
| 64 |
心肌细胞 |
All-Optical and Label- Free Stimulation of Action Potentials in Neurons and Cardiomyocytes by Plasmonic Porous Metamaterials |
等离子体多孔超材料实现神经元与心肌细胞动作电位的全光学无标记刺激 |
2021 |
Advanced Science |
| 65 |
急性脑切片 |
Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice |
Arhgap22 缺失通过 RAC1 过度激活影响海马谷氨酸能突触与认知功能 |
2021 |
Molecular Neurobiology |
| 66 |
类器官 |
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array |
人源皮质兴奋性神经球体在微电极阵列上呈现自发活动特征 |
2021 |
IEEE NER Conference |
| 67 |
神经元培养 |
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells |
基于单层培养系统高效生成人源运动神经元祖细胞及功能运动神经元 |
2021 |
Cells |
| 68 |
急性脑切片 |
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures |
PARP1 过度活化介导 DNA 断裂与神经元钙信号异常导致致死性癫痫的机制研究 |
2021 |
EMBO Reports |
| 69 |
心肌细胞 |
Improving reliability and reducing costs of cardiotoxicity assessments using laser-induced cell poration on microelectrode arrays |
基于激光诱导细胞穿孔的微电极阵列技术提升心脏毒性评估可靠性并降低成本 |
2021 |
Toxicology and Applied Pharmacology |
| 70 |
急性脑切片 |
Sushi domain- containing protein 4 controls synaptic plasticity and motor learning |
SUSD4 蛋白调控突触可塑性与运动学习的分子机制 |
2021 |
eLife |
| 71 |
急性视网膜 |
Transplanted pluripotent stem cell-photoreceptor derived precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration |
多能干细胞来源的光感受器前体移植在晚期视网膜变性小鼠中引发常规与特殊光响应 |
2021 |
Stem Cells Journal |
| 72 |
急性脑切片 |
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions |
谷氨酸能神经元网络中静默但可激活的间隙连接的电学调控机制 |
2020 |
Neuroscience Journal of |
| 73 |
类器官 |
Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids |
常温运输对多能干细胞来源视网膜类器官生物活性的影响研究 |
2020 |
PLOS ONE |
| 74 |
急性脑切片 |
A Claustrum in Reptiles and its role in Slow-Wave Sleep |
爬行动物屏状核的发现及其在慢波睡眠中的调控机制 |
2020 |
Nature |
| 75 |
急性视网膜 |
Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retina |
哺乳动物视网膜异型神经节细胞电耦合的功能解析 |
2020 |
Neuroscience Journal of |
| 76 |
信号处理 |
Neural field models for latent state inference: Application to large-scale neuronal recordings |
基于神经场模型的潜状态推断技术及其在大规模神经元记录中的应用 |
2019 |
PLOS Computational Biology |
| 77 |
急性视网膜 |
Investigating the Effects of Mechanical Stimulation on Retinal Ganglion Cell Spontaneous Spiking Activity |
机械刺激对视网膜神经节细胞自发放电活动的调控机制研究 |
2019 |
Frontiers in Cellular Neuroscience |
| 78 |
神经元培养 |
Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arrays |
基于传递熵的多电极阵列海马培养网络自发放电连接性解析 |
2019 |
IJCNN Conference |
| 79 |
类器官 |
Decellularised extracellular matrix- derived peptides enhance synaptic markers in retinal organoids |
神经视网膜脱细胞基质肽提升人源视网膜类器官突触标记物表达及光响应性 |
2019 |
Biomaterials |
| 80 |
急性脑切片 |
Constitutive Inactivation of the PRRT2 Gene Alters Short-Term Synaptic Plasticity and Promotes Network Hyperexcitability in Hippocampal Neurons |
PRRT2 基因缺失通过短时程突触可塑性异常诱导海马网络超兴奋性 |
2019 |
Cerebral Cortex |
| 81 |
类器官 |
Systematic Comparison of Retinal Organoid Differentiation Methods |
人源多能干细胞视网膜类器官分化方法的系统比较研究 |
2019 |
Stem Cell Transl Med |
| 82 |
急性视网膜 |
Non-parametric Physiological Classification of Retinal Ganglion Cells |
基于非参数方法的视网膜神经节细胞生理分类研究 |
2018 |
Front. Cell. Neurosci. |
| 83 |
急性脑切片 |
High Density MEA as Tool for Convulsant Drug Monitoring |
高密度多电极阵列作为不同惊厥药物诱导癫痫样活动监测工具 |
2018 |
SFN Conference |
| 84 |
类器官 |
3D CNS Models for Motor Neuron Disease Studies |
中枢神经系统 3D 体外模型的构建及其在运动神经元病研究中的应用 |
2018 |
SFN Conference |
| 85 |
急性脑切片 |
Early Appearance and Spread of Fast Ripples in the Hippocampus in a Model of Cortical Traumatic Brain Injury |
皮质创伤性脑损伤模型中海马快速波纹的早期出现与传播机制研究 |
2018 |
Journal of Neuroscience |
| 86 |
类器官 |
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa |
PRPF31 基因可变剪接异常导致纤毛生成障碍与视网膜色素变性的分子机制 |
2018 |
Nature Communications |
| 87 |
信号处理 |
Identification of excitatory-inhibitory links and network topology in large- scale neuronal assemblies from multi-electrode recordings |
基于多电极记录的大规模神经元集群兴奋 - 抑制连接拓扑解析 |
2018 |
PLOS Computational Biology |
| 88 |
心肌细胞 |
Plasmonic meta- electrodes allow intracellular recordings at network level on high-density CMOS- multi-electrode arrays |
等离子体超电极实现高密度 CMOS 多电极阵列上的网络水平胞内记录技术 |
2018 |
Nature Nanotechnology |
| 89 |
技术 |
Exploiting All Programmable SoCs in Neural Signal Analysis: A Closed- Loop Control for Large-Scale CMOS Multielectrode Arrays |
基于全可编程 SoC 的神经信号闭环控制系统开发及其在大规模 CMOS 多电极阵列中的应用 |
2018 |
IEEE TBioCAS |
| 90 |
类器官 |
Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency |
人诱导多能干细胞构建光响应性视网膜类器官的效能差异及其营养依赖性研究 |
2018 |
Stem Cells |
| 91 |
信号处理 |
Spike Train Synchrony Analysis of Neuronal Cultures |
神经元培养网络脉冲序列同步性分析方法 |
2018 |
IJCNN Conference |
| 92 |
急性脑切片 |
Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation |
基于高密度多电极阵列记录浦肯野细胞放电活动的新型化合物验证平台 |
2018 |
FENS Conference |
| 93 |
神经元培养 |
State-dependent representation of stimulus-evoked activity in high-density recordings of neural cultures |
神经培养系统高密度记录中刺激诱发活动的状态依赖性表征机制 |
2018 |
Scientific Reports |
| 94 |
急性视网膜 |
Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells |
消除水平细胞谷氨酸能输入对小鼠视网膜神经节细胞动态范围与感受野组织的调控研究 |
2018 |
Neuroscience Journal of |
| 95 |
技术 |
Fabrication of Multielectrode Arrays for Neurobiology Applications |
神经生物学应用多电极阵列的制备方法研究 |
2018 |
Methods in Molecular Biology |
| 96 |
神经元培养 |
Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome |
22q11.2 缺失综合征中 GABA 极性转换发育异常的机制解析及临床治疗靶点探索 |
2017 |
Scientific Reports |
| 97 |
信号处理 |
SPICODYN: A Toolbox for the Analysis of Neuronal Network Dynamics and Connectivity from Multi-Site Spike Signal Recordings |
SPICODYN 工具包：基于多站点脉冲信号记录的神经元网络动力学与连接性分析平台 |
2017 |
Neuroinformatics |
| 98 |
技术 |
Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks |
局部循环连接的神经元群体驱动神经网络协调自发活动的启动机制 |
2017 |
PLOS Computational Biology |
| 99 |
神经元培养 |
Selective Targeting of Neurons with Inorganic Nanoparticles: Revealing the Crucial Role of Nanoparticle Surface Charge |
无机纳米粒子表面电荷在神经元靶向调控中的关键作用研究 |
2017 |
ACS Nano |
| 100 |
神经元培养 |
High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies |
基于 CMOS-MEA 的 Aβ 诱导神经网络功能障碍高分辨率电生理成像及神经毒性干预研究 |
2017 |
Scientific Reports |
| 101 |
急性脑切片 |
Polyethylene glycol restores axonal conduction after corpus callosum transection |
聚乙二醇修复胼胝体横断后轴突传导功能的机制研究 |
2017 |
Neural Regeneration Research |
| 102 |
信号处理 |
Unsupervised Spike Sorting for Large- Scale, High-Density Multielectrode Arrays |
面向大规模高密度多电极阵列的无监督尖峰信号分类算法开发 |
2017 |
Cell Reports |
| 103 |
急性视网膜 |
Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina |
发育期小鼠视网膜神经节细胞全视网膜光响应特征解析 |
2017 |
Scientific Reports |
| 104 |
神经元培养 |
Propagation and synchronization of reverberatory bursts in developing cultured networks |
发育中培养神经网络回响爆发放电的传播与同步机制研究 |
2016 |
Journal of Computational Neuroscience |
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Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes |
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Large-scale, high-resolution data acquisition system for extracellular recording of electrophysiological activity |
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Experimental investigation on spontaneously active hippocampal cultures recorded by means of high-density MEAs |
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Beam induced deposition of 3D electrodes to improve coupling to cells |
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Active pixel sensor array for high spatio-temporal resolution electrophysiological recordings |
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1. 2014 年 SFN 会议：Large-Scale recording of light-evoked responses in the retinal ganglion cell layer2. 2012 年 SFN 会议：Multi-site electrical stimulation integrated on 4096 high density micro electrode arrays3. 2010 年 INCF 会议：Recording retinal waves with a 4096 electrodes array4. 2009 年 SFN 会议：Active Pixel Sensor Micro Electrode Arrays (APS-MEA) perspectives and challenges5. 2013 年 TRANSDUCERS 会议：Sensing and actuating electrophysiological activity on brain tissue and neuronal cultures |
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